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- The nematode Caenorhabditis elegans (C. elegans), a simple and welldefined genetic model, has gained increasing popularity among scientists to study the molecular mechanism of emerging materials.Nematodes are the most abundant soil-dwelling invertebrates that occupied a key position in terrestrial ecosystem by influencing energy transfer and nutrient cycling. C. elegans, a free-living nematode that feeds on soil microorganisms, is a simple multicellular eukaryote with its genome first completely sequenced and its cell lineage well described. C. elegans has a short life span, is easy to culture in the laboratory, either in aqueous or in soil matrices. Furthermore, the genome of C. elegans showed a high level of conservation with human’s genome .
|Gene Symbol||Gene Name||Application Scope||Accession Number||Primers (5'-3')
|Size [bp]||Tm [℃]||Detection|
|tba-1||Tubulin, alpha family member||
|Y45F10D.4||Putative iron-sulfur cluster assembly enzyme||
|pmp-3||Peroxisomal membrane protein related||
- geNorm method && Related Reference
- NormFinder method && Related Reference
- Comparative ΔCt method && Related Reference
- BestKeeper method && Related Reference
- Name: Yanqiong Zhang
- Email: Panx@ecu.edu
- Institute: Department of Biology, East Carolina University, Greenville, North Carolina, United States of America
Cited by 65 (Based on Google Scholar [2017-06-16])
- Zhang Y, Chen D, Smith M A, et al. Selection of reliable reference genes in Caenorhabditis elegans for analysis of nanotoxicity[J]. PloS one, 2012, 7(3): e31849.
- Murray AR, Kisin E, Leonard SS, Young SH, Kommineni C, et al. Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology 257: 161–171.