Gene:RPL

Experimental Validated ICGs

Species	Gene Synonymous	Application scenarios	Publication	Year
Anastrepha obliqua	Ribosomal protein L18	Different Developmental Stages	Reference genes for accessing differential expression among developmental stages and analysis of differential expression of OBP genes in Anastrepha obliqua	2016
Anguilla anguilla	Ribosomal protein L13	Silvering	Selection of best-performing reference gene products for investigating transcriptional regulation across silvering in the European eel (Anguilla anguilla)	2015
Aphis gossypii	Ribosomal protein L7	Different Developmental Stages & Geographical Populations	Identification and Validation of Reference Genes for the Normalization of Gene Expression Data in qRT-PCR Analysis in Aphis gossypii (Hemiptera: Aphididae).	2016
Bos taurus	Ribosomal protein large P0	Viral Infection	Evaluation of reference genes for qRT-PCR gene expression studies in whole blood samples from healthy and leukemia-virus infected cattle	2013
Brassica oleracea	Ribosomal protein L18	Abiotic Stresses	Identification of suitable qPCR reference genes in leaves of Brassica oleracea under abiotic stresses	2014
Callithrix jacchus	Ribosomal protien,large, PO	Different Tissues	Selection of suitable reference genes for mRNA quantification studies using common marmoset tissues	2013
Canis lupus familiaris	Ribosomal protein L13a, Ribosomal protein L32	Different Disease Groups & Tissues	Development and application of multiple internal reference (housekeeper) gene assays for accurate normalisation of canine gene expression studies	2007
Canis lupus familiaris	Ribosomal protein L8, 60S Ribosomal protein L32, Ribosomal protein L13A	Different Developmental Stages & Tissues	Selection of internal reference genes for normalization of quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis in the canine brain and other organs	2013
Chlamydomonas	60S ribosomal protein L19	Freezing Acclimation	Validation of housekeeping genes for gene expression studies in an ice alga Chlamydomonas during freezing acclimation	2012
Crassostrea gigas	Ribosomal protein L7	Different Developmental Stages	Validation of housekeeping genes as internal controls for studying gene expression during Pacific oyster (Crassostrea gigas) development by quantitative real-time PCR	2013
Danaus plexippus	Ribosomal protein 49	Biotic & Abiotic Stress	Selection of Reference Genes for RT-qPCR Analysis in the Monarch Butterfly, Danaus plexippus (L.), a Migrating Bio-Indicator	2015
Danio rerio	60S ribosomal protein L13a	Different Developmental Stages & Tissues & Abiotic Stress	Genome-wide identification of suitable zebrafish Danio rerio reference genes for normalization of gene expression data by RT-qPCR	2016
Dicentrarchus labrax	Ribosomal protein L13 a	Different Developmental Stages & Tissues	Evaluation of candidate reference genes for QPCR during ontogenesis and of immune-relevant tissues of European seabass (Dicentrarchus labrax)	2009
Diploptera punctata	Ribosomal protein L32	During Gonadotrophic Cycle	Sequencing and validation of housekeeping genes for quantitative real-time PCR during the gonadotrophic cycle of Diploptera punctata	2013
Drosophila melanogaster	Ribosomal protein L32	Physiological Responses	Evaluation of potential reference genes for reverse transcription-qPCR studies of physiological responses in Drosophila melanogaster	2011
Equus caballus	Ribosomal protein L32	Bronchoalveolar Lavage Cells	Evaluation of suitable reference genes for gene expression studies in bronchoalveolar lavage cells from horses with inflammatory airway disease	2011
Felis catus	Ribosomal protein L17, Ribosomal protein L30	Snap-Frozen Tissues	A validation of 10 feline reference genes for gene expression measurements in snap-frozen tissues	2007
Ganoderma lucidum	ribosomal protein L4	Different Tissues & Developmental Stages	Identification and evaluation of reference genes for qRT-PCR normalization in Ganoderma lucidum	2014
Haliotis rufescens	Ribosomal protein L5	Different Tissues	Selection of reference genes as internal controls for gene expression in tissues of red abalone Haliotis rufescens (Mollusca, Vetigastropoda; Swainson, 1822)	2014
Helicoverpa armigera	Ribosomal protein L32, Ribosomal protein L27	Different Biotic and Abiotic conditions	Identification and validation of reference genes for normalization of gene expression analysis using qRT-PCR in Helicoverpa armigera (Lepidoptera: Noctuidae)	2015
Hippoglossus hippoglossus	Ribosomal protein L7	Different Development & Tissues	Evaluation of potential reference genes for real time RT-PCR studies in Atlantic halibut (Hippoglossus Hippoglossus L.); during development, in tissues of healthy and NNV-injected fish, and in anterior kidney leucocytes	2010
Homo sapiens	Ribosomal protein L13a	Glioma	Selection of suitable reference genes for expression analysis in human glioma using RT-qPCR	2015
Homo sapiens	Ribosomal protein L13, Ribosomal protein, large, P0	Metastatic Clear Cell Renal Cell Carcinoma	Identification of a suitable qPCR reference gene in metastatic clear cell renal cell carcinoma	2014
Homo sapiens	Ribosomal protein L13A	Differentiating Human Embryonic Stem Cells	Reference loci for RT-qPCR analysis of differentiating human embryonic stem cells	2013
Homo sapiens	Ribosomal protein L37a	THP-1 Monocyte Differentiation Into Macrophages	Selection of reliable reference genes during THP-1 monocyte differentiation into macrophages	2010
Homo sapiens	Ribosomal protein large P0	Colonic and Vaginal Epithelial Cell Lines	Reference gene selection for qPCR Is dependent on cell type rather than treatment in colonic and vaginal human epithelial cell lines	2014
Homo sapiens	Ribosomal protein L29	Stomach Cancer	Identification of valid reference genes for gene expression studies of human stomach cancer by reverse transcription-qPCR	2010
Homo sapiens	Ribosomal protein L27	Epicardial Adipose Tissue	Validation of reference genes for the relative quantification of gene expression in human epicardial adipose tissue	2012
Homo sapiens	Ribosomal protein S13	Osteoarthritic Articular Cartilage	Reference genes for normalization of gene expression studies in human osteoarthritic articular cartilage	2008
Hyriopsis cumingii	Ribosomal protein L18	During Biomineralization	Identification of housekeeping genes suitable for gene expression analysis in the pearl mussel, Hyriopsis cumingii, during biomineralization	2014
Ipomoea batatas	Ribosomal protein L2	Abiotic Stress	Stable internal reference genes for the normalization of real-time PCR in different sweetpotato cultivars subjected to abiotic stress conditions	2012
Ixodes scapularis	Ribosomal protein L13A	Different Feeding Phases	Validation of internal reference genes for real-time quantitative polymerase chain reaction studies in the tick, Ixodes scapularis (Acari: Ixodidae)	2013
Leptinotarsa decemlineata	Ribosomal protein 18, Ribosomal protein 4	Different Developmental Stages & Insecticide Treatment	Validation of reference genes for expression analysis by quantitative real-time PCR in Leptinotarsa decemlineata	2013
Lucilia cuprina	Acidic ribosomal phosphoprotein PO	Different Developmental Stages	Evaluation of reference genes for real-time PCR quantification of gene expression in the Australian sheep blowfly, Lucilia cuprina	2010
Lucilia sericata	60S acidic ribosomal protein P0	Immune Challenge	Selection and Evaluation of Tissue Specific Reference Genes in Lucilia sericata during an Immune Challenge	2015
Macrobrachium olfersii	Ribosomal protein L8 (RpL8)	Different Developmental Stages	Identification and evaluation of reference genes for expression studies by RT-qPCR during embryonic development of the emerging model organism, Macrobrachium olfersii	2016
Manihot esculenta	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein	Different Tissues & Developmental Stages & Abiotic & Biotic Stress	Validation of Reference Genes for Relative Quantitative Gene Expression Studies in Cassava (Manihot esculenta Crantz) by Using Quantitative Real-Time PCR	2016
Mus musculus	Ribosomal protein L13A	Mammary Glands	Selection and use of reference genes in mouse mammary glands	2010
Mus musculus	Ribosomal protein, large, P0	Uterus in the Peri-Implantation Period	Reference gene selection for real-time quantitative PCR analysis of the mouse uterus in the peri-implantation period	2013
Mus musculus	Ribosomal protein L13a	Different Tissues & Ageing	Normalization of Reverse Transcription Quantitative PCR Data During Ageing in Distinct Cerebral Structures. Molecular neurobiology	2016
Mus musculus	Ribosomal protein L27, Ribosomal protein L41, Ribosomal protein L7-like 1	Skeletal Muscle & Different Genotypes	Evidence based selection of commonly used RT-qPCR reference genes for the analysis of mouse skeletal muscle	2014
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External Links

• NCBI COnserved Protein Domain Family
• WikiPedia
• Pfam