Gene:RPS

Experimental Validated ICGs

Species	Gene Synonymous	Application scenarios	Publication	Year
Anastrepha obliqua	Ribosomal protein S17	Different Developmental Stages	Reference genes for accessing differential expression among developmental stages and analysis of differential expression of OBP genes in Anastrepha obliqua	2016
Apis mellifera	RPS18	Bacterial Challenge	Reference Gene Selection for Insect Expression Studies Using Quantitative Real-Time PCR: The Head of the Honeybee, Apis mellifera, After a Bacterial Challenge	2008
Bubalus bubalis	ribosomal protein S9, ribosomal protein S23	Mammary Epithelial Cells	Identification of suitable housekeeping genes for expression analysis in mammary epithelial cells of buffalo (Bubalus bubalis) during lactation cycle	2012
Canis lupus familiaris	Ribosomal protein S5, Ribosomal protein S19,	Different Developmental Stages & Tissues	Selection of internal reference genes for normalization of quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis in the canine brain and other organs	2013
Casuarina glauca	40S ribosomal protein	Different Tissues & Abiotic Stress	Validation of candidate reference genes for qRT-PCR studies in symbiotic and non-symbiotic Casuarina glauca Sieb. ex Spreng. under salinity conditions	2015
Coffea arabica L	40S ribosomal protein S15	Different Air CO2 Supply & Temperature	Selection and validation of reference genes for accurate RT-qPCR data normalization in Coffea spp. under a climate changes context of interacting elevated CO2 and temperature	2017
Crassostrea gigas	Ribosomal protein S18	Different Developmental Stages	Validation of housekeeping genes as internal controls for studying gene expression during Pacific oyster (Crassostrea gigas) development by quantitative real-time PCR	2013
Cymbidium kanran	RPS3	Abiotic Stress	Evaluation of candidate reference genes for gene expression studies in Cymbidium kanran	2014
Diabrotica virgifera virgifera	ribosomal protein S9	Different Developmental Stages & Tissues	Validation of reference housekeeping genes for gene expression studies in western corn rootworm (Diabrotica virgifera virgifera)	2014
Drosophila melanogaster	Ribosomal protein L32, Ribosomal Protein S20,	Physiological Responses	Evaluation of potential reference genes for reverse transcription-qPCR studies of physiological responses in Drosophila melanogaster	2011
Felis catus	Clone E472 ribosomal protein S7	Snap-Frozen Tissues	A validation of 10 feline reference genes for gene expression measurements in snap-frozen tissues	2007
Helicoverpa armigera	Ribosomal protein S15	Different Biotic and Abiotic conditions	Identification and validation of reference genes for normalization of gene expression analysis using qRT-PCR in Helicoverpa armigera (Lepidoptera: Noctuidae)	2015
Homo sapiens	40S ribosomal protein S23	Breast Cancer	High-throughput identification of reference genes for research and clinical RT-qPCR analysis of breast cancer samples	2013
Homo sapiens	Ribosomal protein S13	Clear Cell Renal Cell Carcinoma	Validation of housekeeping gene and impact on normalized gene expression in clear cell renal cell carcinoma: critical reassessment of YBX3/ZONAB/CSDA expression	2014
Ixodes scapularis	Ribosomal protein S4	Different Feeding Phases	Validation of internal reference genes for real-time quantitative polymerase chain reaction studies in the tick, Ixodes scapularis (Acari: Ixodidae)	2013
Lucilia sericata	40S ribosomal protein S3	Immune Challenge	Selection and Evaluation of Tissue Specific Reference Genes in Lucilia sericata during an Immune Challenge	2015
Macrobrachium olfersii	Ribosomal protein S6 (RpS6)	Different Developmental Stages	Identification and evaluation of reference genes for expression studies by RT-qPCR during embryonic development of the emerging model organism, Macrobrachium olfersii	2016
Musa acuminata	Ribosomal protein S 2	Different Experimental Conditions	Validation of reference genes for RT-qPCR studies of gene expression in banana fruit under different experimental conditions	2011
Nilaparvata lugens	Ribosomal protein S15, Ribosomal protein S11	Different Experimental Conditions	Selection and Evaluation of Potential Reference Genes for Gene Expression Analysis in the Brown Planthopper, Nilaparvata lugens (Hemiptera: Delphacidae) Using Reverse-Transcription Quantitative PCR	2014
Phytophthora parasitica	40S ribosomal protein S3A	Different Developmental Stages	Selection of internal control genes for real-time quantitative RT-PCR assays in the oomycete plant pathogen Phytophthora parasitica	2006
Plutella xylostella	Ribosomal protein S13, Ribosomal protein S23	Different Developmental Stages & Tissues & Abiotic Stress	Exploring valid reference genes for quantitative real-time PCR analysis in Plutella xylostella (Lepidoptera: Plutellidae)	2013
Ruditapes philippinarum	40s Ribosomal Protein s20	Copper Treated	Validation of reference genes for RT-qPCR in marine bivalve ecotoxicology: Systematic review and case study using copper treated primary Ruditapes philippinarum hemocytes	2017
Scophthalmus maximus	RNA polynerase II subunit D	Viral Infection	Selection of normalization factors for quantitative real time RT-PCR studies in Japanese flounder (Paralichthys olivaceus) and turbot (Scophthalmus maximus) under conditions of viral infection	2013
Sesamia inferens	Ribosomal protein S13, Ribosomal protein S20	Different Tissues & Developmental Stages	Exploring valid reference genes for quantitative real-time PCR analysis in Sesamia inferens (Lepidoptera: Noctuidae)	2015
Spodoptera litura	Ribosomal protein S3	Abiotic & Biotic treatments	Identification and validation of reference genes for gene expression analysis using quantitative PCR in Spodoptera litura (Lepidoptera: Noctuidae)	2013
Stenella coeruleoalba	Ribosomal Protein S18	Striped Dolphin Skin	Selection of reference genes for quantitative RT-PCR studies in striped dolphin (Stenella coeruleoalba) skin biopsies	2006
Symbiodinium	Ribosomal protein S4	Abiotic Stress	Validation of housekeeping genes for gene expression studies in Symbiodinium exposed to thermal and light stress	2011
Tribolium castaneum	Ribosomal protein S18, Ribosomal protein S3	Fungal Challenge	Evaluation of quantitative PCR reference genes for gene expression studies in Tribolium castaneum after fungal challenge	2010

External Links

• NCBI COnserved Protein Domain Family
• WikiPedia
• Pfam