Difference between revisions of "ICG:About"

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'''ICG''' is a freely accessible database of '''Internal Control Genes''' for normalization of gene expression data by RT-qPCR. Based on community curation, '''ICG''' is aimed at '''harnessing collective intelligence''' to collect, edit and annotate comprehensive information about  appropriate '''Internal Control Genes''' selected from '''various experimental conditions''' for hundreds of species.
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ICG is a wiki-based knowledgebase of '''internal control genes (or reference genes) for RT-qPCR normalization''' in a variety of species across three domains of life. Based on community curation, ICG harnesses collective intelligence to integrate a comprehensive collection of internal control genes '''curated from a large volume of literatures''' and provides appropriate internal control genes corresponding to specific experimental conditions for both model and non-model organisms.
  
==Slogan==
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=='''Slogan'''==
 
* Nothing great is ever accomplished in isolation. — Yo-Yo Ma
 
* Nothing great is ever accomplished in isolation. — Yo-Yo Ma
 
* Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia
 
* Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia
 
* Contribute your efforts, further our knowledge. — Zhang Zhang, Founder of ScienceWikis
 
* Contribute your efforts, further our knowledge. — Zhang Zhang, Founder of ScienceWikis
  
==Purpose & Aims==
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=='''Purpose & Aims'''==
 
The purpose of ICG is as follows.
 
The purpose of ICG is as follows.
  
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* Build related wiki extensions to ease content accessibility, adding and editing.
 
* Build related wiki extensions to ease content accessibility, adding and editing.
  
==Acknowledgements==
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=='''Acknowledgements'''==
 
{{ICG:Acknowledgements}}
 
{{ICG:Acknowledgements}}
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=='''CITATION'''==
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* Sang J, Wang ZN, Li M, Cao JB, Niu GY, Xia L, Zou D, Wang F, Xu XJ, Han XJ, Fan JQ, Yang Y, Zuo WZ, Zhang Y, Zhao WM, Bao YM, Xiao JF, Hu SN, Hao LL, Zhang Z. [https://academic.oup.com/nar/article/doi/10.1093/nar/gkx875/4282671/ICG-a-wikidriven-knowledgebase-of-internal-control '''ICG: a wiki-driven knowledgebase of internal control genes for RT-qPCR normalization''']. ''Nucleic Acids Research'', 2018 gkx875, doi: 10.1093/nar/gkx875

Latest revision as of 03:02, 8 October 2017

ICG is a wiki-based knowledgebase of internal control genes (or reference genes) for RT-qPCR normalization in a variety of species across three domains of life. Based on community curation, ICG harnesses collective intelligence to integrate a comprehensive collection of internal control genes curated from a large volume of literatures and provides appropriate internal control genes corresponding to specific experimental conditions for both model and non-model organisms.

Slogan

  • Nothing great is ever accomplished in isolation. — Yo-Yo Ma
  • Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia
  • Contribute your efforts, further our knowledge. — Zhang Zhang, Founder of ScienceWikis

Purpose & Aims

The purpose of ICG is as follows.

  • Establish a community-based system to curate RT-qPCR internal control genes across different tissues and different experimental conditions for both model and non-model organisms.
  • Provide up-to-date, comprehensive, and professional informations about internal control genes for molecular biologists to carry out their RT-qPCR experiments.
  • Build related wiki extensions to ease content accessibility, adding and editing.

Acknowledgements

Contributions

We thank a number of users for sharing their valuable knowledge, making edits, sending suggestions and reporting bugs.

Funding

ICG is supported by grants from:

  • Strategic Priority Research Program of the Chinese Academy of Sciences [XDB13040500 and XDA08020102 to Z.Z.; XDA08020102 to S.H.];
  • National Programs for High Technology Research and Development [2015AA020108 and 2012AA020409 to Z.Z.];
  • International Partnership Program of the Chinese Academy of Sciences [153F11KYSB20160008];
  • The 100-Talent Program of Chinese Academy of Sciences [to Y.B and Z.Z.];
  • National Natural Science Foundation of China [31100915 to L.H.].

CITATION